Dimethyltubocurarine
From DrugPedia: A Wikipedia for Drug discovery
| Dimethyltubocurarine
| |
| Systematic (IUPAC) name | |
| N/A | |
| Identifiers | |
| CAS number | ? |
| ATC code | ? |
| PubChem | |
| ChemSpider | |
| Chemical data | |
| Formula | C39H45N2O6+ |
| Mol. mass | 637.7844 |
| SMILES | & |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
[edit] Description
RN given refers to unlabeled parent cpd. This is a neuromuscular blocking agent that act in AchE and inhibit it's activity.This drug combine with receptor site at the post synaptic membrane normally used by acetylcholine and thus block the neurotransmitter action of acetylcholine. Therefore they are referred to as competitive blocking agent since they are competeting for the same receptor site as acetylcholine. As these drug are slowly metabolized, the paralysis pases off.
[edit] General Properties
*Molecular Weight
637.7844
*Molecular Formula
C39H45N2O6+
*IUPAC NAME
N/A
*Canonical Smiles
CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C6C(CC7=CC(=C(O3)C=C7)OC)[N+](CCC6=CC(=C5OC)OC)(C)C)OC
*Isomeric Smiles
CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C6[C@@H](CC7=CC(=C(O3)C=C7)OC)[N+](CCC6=CC(=C5OC)OC)(C)C)OC
*XLogP
N/A
*Topological Polar Surface Area
58.6
