Domesticine

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[edit] Description

The pharmacological profile of (±)-domesticine, a novel α1-adrenoceptor antagonist.

(±)-domesticine is more potent for α1D-adrenoceptor than for α1A- or α1B-adrenoceptor subtypes and it is highly selective compared to 5-HT1A and other receptors.

[edit] General Properties

*Molecular Weight

325.35846

*Molecular Formula

C₁₉H₁₉NO₄

*IUPAC NAME

N/A

*Canonical Smiles

CN1CCC2=CC(=C(C3=C2C1CC4=CC5=C(C=C43)OCO5)O)OC

*Isomeric Smiles

CN1CCC2=CC(=C(C3=C2[C@@H]1CC4=CC5=C(C=C43)OCO5)O)OC

*XLogP

2.8

*Topological Polar Surface Area

51.2

[edit] External Links

• Pubchem

Link to BIAdb Database