Dienestrol
From DrugPedia: A Wikipedia for Drug discovery
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| Dienestrol
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| Systematic (IUPAC) name | |
| 4-[(2E,4E)-4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C18H18O2 |
| Mol. mass | 266.33 |
| SMILES | & |
| Synonyms | alpha-Dienestrol |
| Physical data | |
| Melt. point | 227.5(EXP) °C |
| Solubility in water | 3(EXP) at 37oC mg/mL |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 50 to 80% |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
A synthetic, non-steroidal estrogen structurally related to stilbestrol. It is used, usually as the cream, in the treatment of menopausal and postmenopausal symptoms.
[edit] General Properties
*Molecular Weight
266.33
*Molecular Formula
C18H18O2
*IUPAC NAME
4-[(2E,4E)-4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol
*Canonical Smiles
CC=C(C1=CC=C(C=C1)O)C(=CC)C2=CC=C(C=C2)O
*Isomeric Smiles
CC=C(/C1=CC=C(C=C1)O)C(=CC)C2=CC=C(C=C2)O
[edit] PhysioChemical Properties
*Melting Point
227.5(EXP)
*LogP
5.32(EST)
*Water Solubility
3(EXP) at 37C
