Dienestrol

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Dienestrol
Systematic (IUPAC) name
4-[(2E,4E)-4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol
Identifiers
CAS number	84-17-3
ATC code	?
PubChem	667476
DrugBank	APRD00917
Chemical data
Formula	C18H18O2
Mol. mass	266.33
SMILES	eMolecules & PubChem
Synonyms	alpha-Dienestrol
Physical data
Melt. point	227.5(EXP) °C
Solubility in water	3(EXP) at 37oC mg/mL
Pharmacokinetic data
Bioavailability	?
Protein binding	50 to 80%
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

A synthetic, non-steroidal estrogen structurally related to stilbestrol. It is used, usually as the cream, in the treatment of menopausal and postmenopausal symptoms.

[edit] General Properties

*Molecular Weight

266.33

*Molecular Formula

C₁₈H₁₈O₂

*IUPAC NAME

4-[(2E,4E)-4-(4-hydroxyphenyl)hexa-2,4-dien-3-yl]phenol

*Canonical Smiles

CC=C(C1=CC=C(C=C1)O)C(=CC)C2=CC=C(C=C2)O

*Isomeric Smiles

CC=C(/C1=CC=C(C=C1)O)C(=CC)C2=CC=C(C=C2)O

[edit] PhysioChemical Properties

*Melting Point

227.5(EXP)

*LogP

5.32(EST)

*Water Solubility

3(EXP) at 37C

[edit] External Links

• [1]Pubchem
• [2]]KEGG Compound
• [3]KEGG Drug
• [4]Drugbank