Nuclear receptor subfamily 2 group A member 1;
From DrugPedia: A Wikipedia for Drug discovery
Revision as of 00:00, 15 January 2001 by Special:Contributions/ (Talk)
Contents |
Source Organism
Xenopus laevis (African clawed frog).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.
Subcellular Localization
Nucleus.
Developmental Stage
Maternal protein which is distributed within an animal-to-vegetal gradient in the embryo. Present throughout the entire development.
Similarity
Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Post translational Modification
Function
Transcription factor; binds and activates the promoter for the HNF1-alpha gene. Potential initiator of a transcriptional cascade within a subset of cells committed to a specific developmental program. Could be a determinant for asymmetry in early development.
