Nuclear receptor subfamily 2 group A member 1;

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Contents

[edit] Source Organism

Xenopus laevis (African clawed frog).

[edit] Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;Xenopodinae; Xenopus; Xenopus.

[edit] Subcellular Localization

Nucleus.

[edit] Developmental Stage

Maternal protein which is distributed within an animal-to-vegetal gradient in the embryo. Present throughout the entire development.

[edit] Similarity

Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.

[edit] Post translational Modification

[edit] Function

Transcription factor; binds and activates the promoter for the HNF1-alpha gene. Potential initiator of a transcriptional cascade within a subset of cells committed to a specific developmental program. Could be a determinant for asymmetry in early development.

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