Corticosterone

From DrugPedia: A Wikipedia for Drug discovery

CORTICOSTERONE Pubchem(5753)

An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)

KEGG Pathway(C02140)

• C21-Steroid hormone metabolism

|33346 |1Y5R |Zhang J, Osslund TD, Plant MH, Clogston CL, Nybo RE, Xiong F, Delaney JM, Jordan SRCrystal structure of murine 11 beta-hydroxysteroid dehydrogenase 1: an important therapeutic target for diabetesBiochemistry v44, p.6948-6957

Physical Property Value Units Temp (deg C) Source |Melting Point |181 |deg C | |EXP |- |log P (octanol-water) |1.94 |(none) |EXP |- |Water Solubility |199 |mg/L |25 |EXP |- |Vapor Pressure |4.74E-12 |mm Hg 25 |EST |- |Henry's Law Constant |3.70E-10 |atm-m3/mole |25 |EST |- |Atmospheric OH Rate Constant |1.16E-10 |cm3/molecule-sec |25 |- |}