CarboDB Capsular polysaccharide 1971
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Revision as of 00:00, 15 January 2001 by Special:Contributions/ (Talk)
Carbohydrate Name
Capsular polysaccharide
Carbohydrate Class
Capsular polysaccharide
Source Microbe
Streptococcus pneumoniae strain 6B
Basic Structure
The capsular polysaccharide consists of the following residues : -2)-α-D-Galp-(1-->3)-α-D-Glcp-(1-->3)-α-L-Rhap-(1-->4)-D-Rib-ol-(5-P-
Proposed functions
N/A
Antigenic Nature used to produce antibodies
Glycoconjugates
Carrier Name
Tetanus toxoid
Conjugation Method
The oligosaccharide was derivatized with adipic acid dihydrazide and coupled to tetanus toxoid
Antibodies
Mab 10H8
Antibody type and class
IgG1
Assay System
Enzyme Inhibition Assay, colony blotting, Opsonophagocytosis assay
Cross-reactivity
This Mab reacted with polysaccharides from 11A, 19F and 23F strain but did not recognize type 6A polysaccharide
Proposed epitopes
disaccharide rhamnose-(1-->4)-ribitol phosphate residues seemed to be the part of the epitope
Proposed Utility
N/A
