CarboDB Heptasaccharide motif (M2) of Glucurunoxylomannan 1493

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Contents

Carbohydrate Name

Heptasaccharide motif (M2) of Glucurunoxylomannan

Carbohydrate Class

Miscellaneous

Source Microbe

Cryptococcus neoformans Serotype D [strain 24067]

Basic Structure

The heptasaccharide consists of two M2 triad repeats and mannose residue. The M2 repeat was selected because it is commonly found in GXM of serotype A strain


Proposed functions

Glucurunoxylomannan is an antiphagocytic determinant ; an important virulence factor

Antigenic Nature used to produce antibodies

Glycoconjugates

Carrier Name

Human serum albumin

Conjugation Method

N/A

Antibodies

Mab 1E3

Antibody type and class

IgM

Assay System

Immunofluorescence and phagocytosis assays

Cross-reactivity

This antibody cross-reacted with Serotype D

Proposed epitopes

N/A

Proposed Utility

N/A

Weblink

PubMed

External Links