CarboDB Heptasaccharide motif (M2) of Glucurunoxylomannan 1493
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Revision as of 00:00, 15 January 2001 by Special:Contributions/ (Talk)
Carbohydrate Name
Heptasaccharide motif (M2) of Glucurunoxylomannan
Carbohydrate Class
Miscellaneous
Source Microbe
Cryptococcus neoformans Serotype D [strain 24067]
Basic Structure
The heptasaccharide consists of two M2 triad repeats and mannose residue. The M2 repeat was selected because it is commonly found in GXM of serotype A strain
Proposed functions
Glucurunoxylomannan is an antiphagocytic determinant ; an important virulence factor
Antigenic Nature used to produce antibodies
Glycoconjugates
Carrier Name
Human serum albumin
Conjugation Method
N/A
Antibodies
Mab 1E3
Antibody type and class
IgM
Assay System
Immunofluorescence and phagocytosis assays
Cross-reactivity
This antibody cross-reacted with Serotype D
Proposed epitopes
N/A
Proposed Utility
N/A