From DrugPedia: A Wikipedia for Drug discovery

Imunoatation of Rv0007
Name
POSSIBLE CONSERVED MEMBRANE PROTEIN
Identifiers
Swiss Prot	P71575
Genbank	885982
PDB	?
Chemical data
Formula	C12H10BrNOS2 [1]
Mol. wt.	31073 Da
Pharmacokinetic data
Bioavailability	?
Solubility	?
Isoelectric-Point	9.17

Contents 1 General 1.1 Protein Sequence 2 Human Homologue Blast Result 3 Alergen Protein 4 Bacterial Toxin Prediction 5 Subcellular Location 6 Antigens 6.1 B cell Epitopes 6.1.1 BCEpred Analysis 6.1.2 ABCpred Analysis 6.1.3 IEDB Analysis 7 MHC Class-I Binder 7.1 nHLAPred Analysis 7.2 IEDB Analysis 8 MHC Class-II Binder 8.1 Propred Analysis 8.2 NetMHC-II Analysis 9 External Links

General

Hypothetical protein, Possible conserved membrane protein and highly similar to the Z70722|MLCB1770_7 Mycobacterium leprae cosmid B1770 (303 aa), FASTA scores: opt: 812, E(): 1.6e-25, (54.2% identity in 319 aa overlap). Non essential for optimal growth.(http://www.biohealthbase.org/brc/details.do?locus=Rv0007&decorator=mycobacterium)

Protein Sequence

>Rv0007, TB.seq 9914:10825 MW:31042 VTAPNEPGALSKGDGPNADGLVDRGGAHRAATGPGRIPDAGDPPPWQRAATRQSQAGHRQPPPVSHPEGRPTNPPAAADA RLNRFISGASAPVTGPAAAVRTPQPDPDASLGCGDGSPAEAYASELPDLSGPTPRAPQRNPAPARPAEGGAGSRGDSAAG SSGGRSITAESRDARVQLSARRSRGPVRASMQIRRIDPWSTLKVSLLLSVALFFVWMITVAFLYLVLGGMGVWAKLNSNV GDLLNNASGSSAELVSSGTIFGGAFLIGLVNIVLMTALATIGAFVYNLITDLIGGIEVTLADRD

Human Homologue Blast Result

subject ids	% identity	% positives	alignment length	evalue
|sp|Q9Y4K1.3	26	32	176	0.061
sp|O75962.2	27	33	151	0.067
sp|Q13029.3	29	39	89	0.13
sp|Q9Y6V0.3	25	35	120	0.28
sp|Q6IQ32.1	27	40	86	0.46

Alergen Protein

Link to Algpred
Non Allergen Predicted by AlgPred Server

Bacterial Toxin Prediction

Link to btxpred
No Hit Fountd by btxpred server.

Subcellular Location

Link to TBpred
Integral Membrane

Antigens

No Hit Found in AntigenDB
No. Hit Found in IEDB

B cell Epitopes

BCEpred Analysis

Link to Bcepred
Result Predicited by [2]

ABCpred Analysis

Link to ABCpred
Result Predicited by [3]<

IEDB Analysis

Link to IEDB
Result Predicited by

MHC Class-I Binder

nHLAPred Analysis

Link to nHLApred
Result Predicited by [4]

IEDB Analysis

Link to IEDB
Result Predicted by

MHC Class-II Binder

Propred Analysis

Link to Propred
Result Predicted by

NetMHC-II Analysis

Link to NetMHC-II
Result Predicted by

External Links

• Database of Mycobacterium tuberculosis genome sequences and related information.