Diiodotyrosine

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

A product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or diiodotyrosine residues to form T4 or T3 thyroid hormones (THYROXINE and TRIIODOTHYRONINE).

General Properties

*Molecular Weight

432.98

*Molecular Formula

C₉H₉I₂NO₃

*IUPAC NAME

(2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid

*Canonical Smiles

C1=C(C=C(C(=C1I)O)I)CC(C(=O)O)N

*Isomeric Smiles

C1=C(C=C(C(=C1I)O)I)C[C@@H](C(=O)O)N

PhysioChemical Properties

*Melting Point

*LogP

0.57(EST)

*Water Solubility

617(EXP) at 25C

External Links

• [1]Pubchem
• [2]KEGG Compound
• [3]Human Metabolome DataBase

Categories:Hormones