Diiodotyrosine

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Diiodotyrosine
Systematic (IUPAC) name
(2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid
Identifiers
CAS number	66-02-4
ATC code	?
PubChem	9305
Chemical data
Formula	C9H9I2NO3
Mol. mass	432.98
SMILES	eMolecules & PubChem
Synonyms	L-Diiodotyrosine
Physical data
Solubility in water	617(EXP) at 25oC mg/mL
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

A product from the iodination of MONOIODOTYROSINE. In the biosynthesis of thyroid hormones, diiodotyrosine residues are coupled with other monoiodotyrosine or diiodotyrosine residues to form T4 or T3 thyroid hormones (THYROXINE and TRIIODOTHYRONINE).

[edit] General Properties

*Molecular Weight

432.98

*Molecular Formula

C₉H₉I₂NO₃

*IUPAC NAME

(2S)-2-amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid

*Canonical Smiles

C1=C(C=C(C(=C1I)O)I)CC(C(=O)O)N

*Isomeric Smiles

C1=C(C=C(C(=C1I)O)I)C[C@@H](C(=O)O)N

[edit] PhysioChemical Properties

*Melting Point

*LogP

0.57(EST)

*Water Solubility

617(EXP) at 25C

[edit] External Links

• [1]Pubchem
• [2]KEGG Compound
• [3]Human Metabolome DataBase