Corticosterone

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)

General Properties

*Molecular Weight

346.46

*Molecular Formula

C₂₁H₃₀O₄

*IUPAC NAME

(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4C(=O)CO)C)O

*Isomeric Smiles

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C)O

PhysioChemical Properties

*Melting Point

181(EXP)

*LogP

1.94(EXP)

*Water Solubility

199(EXP) at 25C

External Links

• [1]Pubchem
• [2]]1Y5R,
• [3]]KEGG Compound
• [4]Human Metabolome DataBase

Categories:Hormones