Prednisone
From DrugPedia: A Wikipedia for Drug discovery
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==Description== | ==Description== | ||
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A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver. | A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver. | ||
==General Properties== | ==General Properties== | ||
Revision as of 09:31, 19 February 2009
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Description
A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.
General Properties
*Molecular Weight
358.43
*Molecular Formula
C21H26O5
*IUPAC NAME
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
*Canonical Smiles
CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C
*Isomeric Smiles
C[C@]12CC(=O)[C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C
PhysioChemical Properties
*Melting Point
234(EXP)
*LogP
1.46(EXP)
*Water Solubility
312(EST) at 25C
