Prednisone

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

[edit] Description

Show 3-D Structure

A synthetic anti-inflammatory glucocorticoid derived from CORTISONE. It is biologically inert and converted to PREDNISOLONE in the liver.

[edit] General Properties

*Molecular Weight

358.43

*Molecular Formula

C₂₁H₂₆O₅

*IUPAC NAME

(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

*Canonical Smiles

CC12CC(=O)C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C

*Isomeric Smiles

C[C@]12CC(=O)[C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C

[edit] PhysioChemical Properties

*Melting Point

234(EXP)

*LogP

1.46(EXP)

*Water Solubility

312(EST) at 25C

[edit] External Links

• [1]Pubchem
• [2]KEGG Compound
• [3]Drugbank