11-Deoxycortisol

(Difference between revisions)

Revision as of 08:58, 1 November 2008

Cortexolone Pubchem(440707)

17,21-Dihydroxypregn-4-ene-3,20-dione. A 17-hydroxycorticosteroid with glucocorticoid and anti-inflammatory activities.

KEGG Pathway(C05488,D03595)

Activity Anti-inflammatory

**Physiochemical properties of Estriol:**
Physical Property	Value	Units	Temp (deg C)	Source
Melting Point	215	deg C		EXP
log P (octanol-water)	3.08	(none)		EXP
Water Solubility	15.2	mg/L	25	EST
Vapor Pressure	9.49E-12	mm Hg	25	EST
Henry's Law Constant	1.58E-06	atm-m3/mole	25	EST
Atmospheric OH Rate Constant	1.05E-10	cm3/molecule-sec	25	EST

**Toxicity:**
Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	intravenous	100mg/kg (100mg/kg)	U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04684,

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 |}
-Organism  	Test Type  	Route  	Reported Dose (Normalized Dose)  	Effect  	Source
+{| border="1;width:100%; height:200px;style=text-align:center"
+|+'''Toxicity:'''
+|-
+! style="background:brown; color:white" |Organism
+! style="background:brown; color:white" |Test Type
+! style="background:brown; color:white" |Route
+! style="background:brown; color:white" |Reported Dose (Normalized Dose)
+! style="background:brown; color:white" |Effect
+! style="background:brown; color:white" |Source
+|-
 |mouse
 |LD50