Corticosterone

From DrugPedia: A Wikipedia for Drug discovery

(Difference between revisions)
Jump to: navigation, search
Line 53: Line 53:
|cm3/molecule-sec
|cm3/molecule-sec
|25
|25
 +
|EST
|-
|-
|}
|}

Revision as of 08:29, 30 October 2008

CORTICOSTERONE Pubchem(5753)

An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)

KEGG Pathway(C02140)

  • C21-Steroid hormone metabolism

|33346 |1Y5R |Zhang J, Osslund TD, Plant MH, Clogston CL, Nybo RE, Xiong F, Delaney JM, Jordan SRCrystal structure of murine 11 beta-hydroxysteroid dehydrogenase 1: an important therapeutic target for diabetesBiochemistry v44, p.6948-6957

Physiochemical properties of Estradiol:
Physical Property Value Units Temp (deg C) Source
Melting Point 181 deg C EXP
log P (octanol-water) 1.94 (none) EXP
Water Solubility 199 mg/L 25 EXP
Vapor Pressure 4.74E-12 mm Hg 25 EST
Henry's Law Constant 3.70E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.16E-10 cm3/molecule-sec 25 EST