PolysacDB Lipopolysaccharide 1191

From DrugPedia: A Wikipedia for Drug discovery

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Revision as of 06:03, 8 April 2010

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Yersinia enterocolitica 0:9

Basic Structure

The O-antigen part consists of the following residues : -2)-α-D-Rhap4NFo-(1-

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Killed whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Ys.T9-7

Antibody type and class

IgG2a

Assay System

Whole cell agglutination, immunodiffusion, immunoblotting and ELISA

Cross-reactivity

This Mab agglutinated Yersinia and Brucella abortus cells and had high ELISA titers, but which failed to precipitate the polysaccharide antigens

Proposed epitopes

The epitope was proposed to be Terminal nonreducing portions of the O-chain

Proposed Utility

This Mab can be used to study the cell wall polysaccharide antigens of other Y. enterocolitica strains and are being evaluated for specific serological identification of B. abortus.

Weblink

PubMed Central

External Links

• Link to PolysacDB database