PolysacDB Lipopolysaccharide 1191

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Yersinia enterocolitica 0:9

[edit] Basic Structure

The O-antigen part consists of the following residues : -2)-α-D-Rhap4NFo-(1-

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Killed whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Ys.T9-7

[edit] Antibody type and class

IgG2a

[edit] Assay System

Whole cell agglutination, immunodiffusion, immunoblotting and ELISA

[edit] Cross-reactivity

This Mab agglutinated Yersinia and Brucella abortus cells and had high ELISA titers, but which failed to precipitate the polysaccharide antigens

[edit] Proposed epitopes

The epitope was proposed to be Terminal nonreducing portions of the O-chain

[edit] Proposed Utility

This Mab can be used to study the cell wall polysaccharide antigens of other Y. enterocolitica strains and are being evaluated for specific serological identification of B. abortus.

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database