CarboDB Cell wall antigen (SA I/II) 2405

From DrugPedia: A Wikipedia for Drug discovery

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Revision as of 00:00, 15 January 2001

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

Carbohydrate Name

Cell wall antigen (SA I/II)

Carbohydrate Class

Miscellaneous

Source Microbe

Streptococcus mutans serotype c

Basic Structure

N/A

Proposed functions

N/A

Antigenic Nature used to produce antibodies

Cell wall antigen (SA I/II)

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab Guy 1

Antibody type and class

IgG2a

Assay System

solid-phase radioimmunoassy, Competitive inhibition experiments

Cross-reactivity

This Mab was raised against specific carbohydrate epitopes on the SA and not against contaminating c polysaccharide in the SA preparation and was specific to serotype c

Proposed epitopes

glucose is part of the epitopes of SA recognized by this Mab

Proposed Utility

his Mab can be used in local passive immunization to prevent colonization of S. mutans and the development of caries in monkeys and to prevent colonization of S. mutans in human subjects

Weblink

PubMed

External Links

• Link to CarboDB database