CarboDB Cell wall antigen (SA I/II) 2405
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Cell wall antigen (SA I/II)
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Streptococcus mutans serotype c
[edit] Basic Structure
N/A
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Cell wall antigen (SA I/II)
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab Guy 1
[edit] Antibody type and class
IgG2a
[edit] Assay System
solid-phase radioimmunoassy, Competitive inhibition experiments
[edit] Cross-reactivity
This Mab was raised against specific carbohydrate epitopes on the SA and not against contaminating c polysaccharide in the SA preparation and was specific to serotype c
[edit] Proposed epitopes
glucose is part of the epitopes of SA recognized by this Mab
[edit] Proposed Utility
his Mab can be used in local passive immunization to prevent colonization of S. mutans and the development of caries in monkeys and to prevent colonization of S. mutans in human subjects
