11-Deoxycortisol
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
(New page: '''Cortexolone''' Pubchem(440707) 17,21-Dihydroxypregn-4-ene-3,20-dione. A 17-hydroxycorticosteroid with glucocorticoid and anti-inflammatory activities. '''KEGG Pathway'''(C05488,D0359...) |
|||
| Line 8: | Line 8: | ||
Activity Anti-inflammatory | Activity Anti-inflammatory | ||
| - | + | {| border="1;width:100%; height:200px;style=text-align:center" | |
| - | Physical Property | + | |+'''Physiochemical properties of Estriol:''' |
| + | |- | ||
| + | ! style="background:brown; color:white" |Physical Property | ||
| + | ! style="background:brown; color:white" |Value | ||
| + | ! style="background:brown; color:white" |Units | ||
| + | ! style="background:brown; color:white" |Temp (deg C) | ||
| + | ! style="background:brown; color:white" |Source | ||
| + | |- | ||
|Melting Point | |Melting Point | ||
|215 | |215 | ||
Revision as of 08:57, 1 November 2008
Cortexolone Pubchem(440707)
17,21-Dihydroxypregn-4-ene-3,20-dione. A 17-hydroxycorticosteroid with glucocorticoid and anti-inflammatory activities.
KEGG Pathway(C05488,D03595)
- C21-Steroid hormone metabolism
Activity Anti-inflammatory
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 215 | deg C | EXP | |
| log P (octanol-water) | 3.08 | (none) | EXP | |
| Water Solubility | 15.2 | mg/L | 25 | EST |
| Vapor Pressure | 9.49E-12 | mm Hg | 25 | EST |
| Henry's Law Constant | 1.58E-06 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 1.05E-10 | cm3/molecule-sec | 25 | EST |
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source |mouse |LD50 |intravenous |100mg/kg (100mg/kg) |U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#04684, |}
