20-alpha-dihydroprogesterone
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
(New page: '''Dihydrogesterone''' Pubchem(8956) A biologically active 20-alpha-reduced metabolite of PROGESTERONE. It is converted from progesterone to 20-alpha-hydroxypregn-4-en-3-one by the 20-ALP...) |
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'''KEGG Pathway'''(C04042,C03965) | '''KEGG Pathway'''(C04042,C03965) | ||
*C21-Steroid hormone metabolism | *C21-Steroid hormone metabolism | ||
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|24630 | |24630 | ||
|1MRQ | |1MRQ | ||
Current revision
Dihydrogesterone Pubchem(8956)
A biologically active 20-alpha-reduced metabolite of PROGESTERONE. It is converted from progesterone to 20-alpha-hydroxypregn-4-en-3-one by the 20-ALPHA-HYDROXYSTEROID DEHYDROGENASE in the CORPUS LUTEUM and the PLACENTA.
KEGG Pathway(C04042,C03965)
- C21-Steroid hormone metabolism
| MMDB ID | PDB ID | Reference |
|---|---|---|
| 24630 | 1MRQ | Couture JF, Legrand P, Cantin L, Luu-The V, Labrie F, Breton RHuman 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroidsJ. Mol. Biol. v331, p.593-604 |
