20-alpha-dihydroprogesterone
From DrugPedia: A Wikipedia for Drug discovery
Dihydrogesterone Pubchem(8956)
A biologically active 20-alpha-reduced metabolite of PROGESTERONE. It is converted from progesterone to 20-alpha-hydroxypregn-4-en-3-one by the 20-ALPHA-HYDROXYSTEROID DEHYDROGENASE in the CORPUS LUTEUM and the PLACENTA.
KEGG Pathway(C04042,C03965)
- C21-Steroid hormone metabolism
| MMDB ID | PDB ID | Reference |
|---|---|---|
| 24630 | 1MRQ | Couture JF, Legrand P, Cantin L, Luu-The V, Labrie F, Breton RHuman 20alpha-hydroxysteroid dehydrogenase: crystallographic and site-directed mutagenesis studies lead to the identification of an alternative binding site for C21-steroidsJ. Mol. Biol. v331, p.593-604 |
