Corticosterone

From DrugPedia: A Wikipedia for Drug discovery

(Difference between revisions)
Jump to: navigation, search
Line 10: Line 10:
|1Y5R
|1Y5R
|Zhang J, Osslund TD, Plant MH, Clogston CL, Nybo RE, Xiong F, Delaney JM, Jordan SRCrystal structure of murine 11 beta-hydroxysteroid dehydrogenase 1: an important therapeutic target for diabetesBiochemistry v44, p.6948-6957
|Zhang J, Osslund TD, Plant MH, Clogston CL, Nybo RE, Xiong F, Delaney JM, Jordan SRCrystal structure of murine 11 beta-hydroxysteroid dehydrogenase 1: an important therapeutic target for diabetesBiochemistry v44, p.6948-6957
-
 
+
{| border="1;width:100%; height:200px;style=text-align:center"
-
Physical Property Value Units Temp (deg C) Source
+
|+'''Physiochemical properties of Estradiol:'''
 +
|-
 +
! style="background:brown; color:white" |Physical Property
 +
! style="background:brown; color:white" |Value
 +
! style="background:brown; color:white" |Units  
 +
! style="background:brown; color:white" |Temp (deg C)
 +
! style="background:brown; color:white" |Source
 +
|-
|Melting Point
|Melting Point
|181
|181
Line 20: Line 27:
|log P (octanol-water)
|log P (octanol-water)
|1.94
|1.94
-
|(none)  
+
|(none)
 +
|  
|EXP
|EXP
|-
|-
Line 31: Line 39:
|Vapor Pressure
|Vapor Pressure
|4.74E-12
|4.74E-12
-
|mm Hg 25
+
|mm Hg
 +
|25
|EST
|EST
|-
|-

Revision as of 08:29, 30 October 2008

CORTICOSTERONE Pubchem(5753)

An adrenocortical steroid that has modest but significant activities as a mineralocorticoid and a glucocorticoid. (From Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1437)

KEGG Pathway(C02140)

  • C21-Steroid hormone metabolism

|33346 |1Y5R |Zhang J, Osslund TD, Plant MH, Clogston CL, Nybo RE, Xiong F, Delaney JM, Jordan SRCrystal structure of murine 11 beta-hydroxysteroid dehydrogenase 1: an important therapeutic target for diabetesBiochemistry v44, p.6948-6957

Physiochemical properties of Estradiol:
Physical Property Value Units Temp (deg C) Source
Melting Point 181 deg C EXP
log P (octanol-water) 1.94 (none) EXP
Water Solubility 199 mg/L 25 EXP
Vapor Pressure 4.74E-12 mm Hg 25 EST
Henry's Law Constant 3.70E-10 atm-m3/mole 25 EST
Atmospheric OH Rate Constant 1.16E-10 cm3/molecule-sec 25