Imunoatation of Rv0007
From DrugPedia: A Wikipedia for Drug discovery
| (6 intermediate revisions not shown.) | |||
| Line 14: | Line 14: | ||
}} | }} | ||
=General= | =General= | ||
| - | Hypothetical protein, Possible conserved membrane protein and highly similar to the Z70722|MLCB1770_7 Mycobacterium leprae cosmid B1770 (303 aa), FASTA scores: opt: 812, E(): 1.6e-25, (54.2% identity in 319 aa overlap). Non essential for optimal growth.(http://www.biohealthbase.org/brc/details.do?locus=Rv0007&decorator=mycobacterium) | + | Hypothetical protein, No PDB structure available, Possible conserved membrane protein and highly similar to the Z70722|MLCB1770_7 Mycobacterium leprae cosmid B1770 (303 aa), FASTA scores: opt: 812, E(): 1.6e-25, (54.2% identity in 319 aa overlap). Non essential for optimal growth.(http://www.biohealthbase.org/brc/details.do?locus=Rv0007&decorator=mycobacterium) |
==Protein Sequence== | ==Protein Sequence== | ||
| Line 58: | Line 58: | ||
Link to [http://www.imtech.res.in/raghava/bcepred/bcepred_submission.html Bcepred] | Link to [http://www.imtech.res.in/raghava/bcepred/bcepred_submission.html Bcepred] | ||
<br> | <br> | ||
| - | Result Predicited by [http://crdd.osdd.net/drugpedia/images/ | + | Result Predicited by [http://crdd.osdd.net/drugpedia/images/BcePred.pdf]<br> |
====ABCpred Analysis==== | ====ABCpred Analysis==== | ||
Link to [http://www.imtech.res.in/raghava/abcpred/ABC_submission.html ABCpred]<br> | Link to [http://www.imtech.res.in/raghava/abcpred/ABC_submission.html ABCpred]<br> | ||
| - | Result Predicited by | + | Result Predicited by [http://crdd.osdd.net/drugpedia/images/ABCpred.pdf]< <br> |
====IEDB Analysis==== | ====IEDB Analysis==== | ||
Link to [http://tools.immuneepitope.org/tools/bcell/iedb_input IEDB]<br> | Link to [http://tools.immuneepitope.org/tools/bcell/iedb_input IEDB]<br> | ||
| - | Result Predicited by <br> | + | Result Predicited by [http://crdd.osdd.net/drugpedia/images/IEDB.pdf]<<br> |
=MHC Class-I Binder= | =MHC Class-I Binder= | ||
| Line 72: | Line 72: | ||
Link to [http://www.imtech.res.in/raghava/nhlapred/comp.html nHLApred] | Link to [http://www.imtech.res.in/raghava/nhlapred/comp.html nHLApred] | ||
<br> | <br> | ||
| - | Result Predicited by <br> | + | Result Predicited by [http://crdd.osdd.net/drugpedia/images/NHLAPred.pdf]<br> |
==IEDB Analysis== | ==IEDB Analysis== | ||
Link to [http://tools.immuneepitope.org/analyze/html/mhc_processing.html IEDB] <br> | Link to [http://tools.immuneepitope.org/analyze/html/mhc_processing.html IEDB] <br> | ||
| - | Result Predicted by | + | Result Predicted by [http://crdd.osdd.net/drugpedia/images/IED.pdf]<br> |
=MHC Class-II Binder= | =MHC Class-II Binder= | ||
==Propred Analysis== | ==Propred Analysis== | ||
Link to [http://www.imtech.res.in/raghava/propred/ Propred]<br> | Link to [http://www.imtech.res.in/raghava/propred/ Propred]<br> | ||
| - | Result Predicted by | + | Result Predicted by [http://crdd.osdd.net/drugpedia/images/PROPRED.pdf]<br> |
==NetMHC-II Analysis== | ==NetMHC-II Analysis== | ||
Link to [http://www.cbs.dtu.dk/services/NetMHCII/ NetMHC-II]<br> | Link to [http://www.cbs.dtu.dk/services/NetMHCII/ NetMHC-II]<br> | ||
| - | Result Predicted by | + | Result Predicted by [http://crdd.osdd.net/drugpedia/images/NETMHC.pdf]<br> |
=External Links= | =External Links= | ||
Current revision
| Imunoatation of Rv0007
| |
| Name | |
| POSSIBLE CONSERVED MEMBRANE PROTEIN | |
| Identifiers | |
| Swiss Prot | |
| Genbank | |
| PDB | ? |
| Chemical data | |
| Formula | C12H10BrNOS2 [1] |
| Mol. wt. | 31073 Da |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Solubility | ? |
| Isoelectric-Point | 9.17 |
Contents |
[edit] General
Hypothetical protein, No PDB structure available, Possible conserved membrane protein and highly similar to the Z70722|MLCB1770_7 Mycobacterium leprae cosmid B1770 (303 aa), FASTA scores: opt: 812, E(): 1.6e-25, (54.2% identity in 319 aa overlap). Non essential for optimal growth.(http://www.biohealthbase.org/brc/details.do?locus=Rv0007&decorator=mycobacterium)
[edit] Protein Sequence
>Rv0007, TB.seq 9914:10825 MW:31042 VTAPNEPGALSKGDGPNADGLVDRGGAHRAATGPGRIPDAGDPPPWQRAATRQSQAGHRQPPPVSHPEGRPTNPPAAADA RLNRFISGASAPVTGPAAAVRTPQPDPDASLGCGDGSPAEAYASELPDLSGPTPRAPQRNPAPARPAEGGAGSRGDSAAG SSGGRSITAESRDARVQLSARRSRGPVRASMQIRRIDPWSTLKVSLLLSVALFFVWMITVAFLYLVLGGMGVWAKLNSNV GDLLNNASGSSAELVSSGTIFGGAFLIGLVNIVLMTALATIGAFVYNLITDLIGGIEVTLADRD
[edit] Human Homologue Blast Result
| subject ids | % identity | % positives | alignment length | evalue |
| |sp|Q9Y4K1.3 | 26 | 32 | 176 | 0.061 |
| sp|O75962.2 | 27 | 33 | 151 | 0.067 |
| sp|Q13029.3 | 29 | 39 | 89 | 0.13 |
| sp|Q9Y6V0.3 | 25 | 35 | 120 | 0.28 |
| sp|Q6IQ32.1 | 27 | 40 | 86 | 0.46 |
[edit] Alergen Protein
Link to Algpred
Non Allergen Predicted by AlgPred Server
[edit] Bacterial Toxin Prediction
Link to btxpred
No Hit Fountd by btxpred server.
[edit] Subcellular Location
Link to TBpred
Integral Membrane
[edit] Antigens
No Hit Found in AntigenDB
No. Hit Found in IEDB
[edit] B cell Epitopes
[edit] BCEpred Analysis
Link to Bcepred
Result Predicited by [2]
[edit] ABCpred Analysis
Link to ABCpred
Result Predicited by [3]<
[edit] IEDB Analysis
Link to IEDB
Result Predicited by [4]<
[edit] MHC Class-I Binder
[edit] nHLAPred Analysis
Link to nHLApred
Result Predicited by [5]
[edit] IEDB Analysis
Link to IEDB
Result Predicted by [6]
[edit] MHC Class-II Binder
[edit] Propred Analysis
Link to Propred
Result Predicted by [7]
[edit] NetMHC-II Analysis
Link to NetMHC-II
Result Predicted by [8]
[edit] External Links
- Database of Mycobacterium tuberculosis genome sequences and related information.
