Testicular receptor 2

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Source Organism 2 Taxomomy 3 Subcellular Localization 4 Developmental Stage 5 Similarity 6 Post translational Modification 7 Function

[edit] Source Organism

Homo sapiens (Human).

[edit] Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.

[edit] Subcellular Localization

Nucleus (Potential).

[edit] Developmental Stage

[edit] Similarity

Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.

[edit] Post translational Modification

[edit] Function

Orphan nuclear receptor. Represses transcription and binds DNA as a homodimer. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism (By similarity).