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- Targeted Drug Delivery superior to molecular manipulations aimed at refining the receptor substrate interactions.4 KB (602 words) - 13:27, 5 November 2011
- Combinatorial Chemistry ... f luminescent materials obtained by co-deposition of elements on a silicon substrate. Work has been continued by several academic groups as well as companies w ...5 KB (795 words) - 05:10, 9 September 2008
- Lysergic acid diethylamide (LSD) LSD is typically delivered orally, usually on a substrate such as absorbent blotter paper, a sugar cube, or gelatin. In its liquid f ...2 KB (305 words) - 09:38, 11 August 2008
- Ticrynafen Tienilic acid was found to act as a suicide substrate at the cytochrome P450 enzymes involved in drug metabolism. Unfortunately, ...1 KB (204 words) - 09:43, 11 August 2008
- Drug targets ... ccur at significant rates. Since enzymes are extremely selective for their substrates and speed up only a few reactions from among many possibilities, the set ... ... d by temperature, chemical environment (e.g. pH), and the concentration of substrate. Some enzymes are used commercially, for example, in the synthesis of anti ...7 KB (1041 words) - 05:38, 17 September 2008
- DNA ... t|255px|The [[restriction enzyme]] [[EcoRV]] (green) in a complex with its substrate DNA<ref>Created from [http://www.rcsb.org/pdb/explore/explore.do?structure ...82 KB (11827 words) - 06:08, 20 August 2008
- Synthetic biology ... mation on naturally occurring organisms. This information provides a rich substrate from which synthetic biologists can construct parts and devices. Second, ... ... c biology will benefit from better models of how biological molecules bind substrates and catalyze reactions, how DNA encodes the information needed to specify ...17 KB (2568 words) - 06:47, 17 September 2008
- HB plot ... and electrons from [[NADPH cytochrome P450 reductase]] to oxidize their [[substrate]]s. [[CYP2B4]], a member of the [[cytochrome P450]] family is the only pro ... The first step in [[P450]] [[catalytic cycle]] is identified as substrate binding. Preliminary binding of a ligand near to the entrance breaks hydro ...8 KB (1156 words) - 09:51, 17 September 2008
- Nonribosomal peptide === Substrate specificities === ... have been identified. The condensation C-domain is also believed to have substrate specificity, especially if located behind an epimerase E-domain-containing ...9 KB (1134 words) - 09:44, 17 September 2008
- Pharmacodynamics ... Antacid]]s and [[chelating agent]]s combine chemically in the body. Enzyme-substrate binding is a way to alter the production or metabolism of key [[endogenous ...8 KB (1104 words) - 17:10, 29 August 2008
- Natural product drug discovery ... pharmacophore or compounds otherwise designed to mimic the natural ligand/substrate of the target). For certain therapy areas, such as antimicrobials, antican ...13 KB (1907 words) - 06:09, 17 September 2008
- Site directed mutagenesis ... uplex fragments. The other hybrid with a 5’-hydroxyl group cannot act as substrate for polymerase, is effectively lost from the reaction mixture. Thus the ov ... ... of this serine protease has been altered including its rate of catalysis, substrate specificity, pH rate profile, and stability to oxidative, thermal and alka ...12 KB (1824 words) - 05:04, 9 September 2008
- Hormone |Androstenedione ||Theca cells ||Substrate for estrogen33 KB (4458 words) - 05:05, 14 October 2008
- Design patent ... stantial practical utility (e.g. a statue) or be separable from the useful substrate (e.g. picture on a coffee mug).6 KB (1045 words) - 04:57, 13 September 2008
- Cellulase ... a flexible linker. This structure is adaption for working on an insoluble substrate and it allows the enzyme to diffuse two-dimensionally on a surface in a ca ...4 KB (599 words) - 09:02, 16 September 2008
- Analysis of Metabolic ‘Choke’ and ‘Load’ points as Drug Targets in Pathogenic Bacteria ... g such chokepoint reactions would result in the accumulation of the unique substrate which is potentially toxic to the cell or in the starvation of the unique ...3 KB (480 words) - 12:38, 27 September 2008
- Erythritol ... uchi, T., Oda, T., and Ideda, T. 1992. Noncariogenicity of erythritol as a substrate. Caries Research 26:358-362. Entrez PubMed 14681006 KB (938 words) - 05:22, 11 October 2008
- Glutathione GSH is known as a substrate in both conjugation reactions and reduction reactions, catalyzed by glutat ...6 KB (856 words) - 04:41, 24 October 2008
- Progestrone ... ortant in the binding of coenzyme, steroids, nitroaromatic ligands and the substrate 2-cyclohexen-1-one....8 KB (1073 words) - 09:35, 19 February 2009
- Androstenedione ... ood by [[theca cells]]. The function of this is to provide androstenedione substrate for [[estrogen]] production in [[granulosa cells]], since these cells lack ...8 KB (1035 words) - 03:46, 20 February 2009
