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  • Drug Discovery
    o Receptors * Some target classes, for example, the G-protein coupled receptors (GPCRs), have been successfully targeted, and a sizable number of drugs pr ...
    23 KB (3467 words) - 03:48, 1 September 2008
  • Target Identification
    #Receptors
    3 KB (452 words) - 06:49, 11 August 2008
  • Immunogenicity Versus Antigenicity
    and/or cell-surface receptors). Although all molecules that
    1 KB (162 words) - 09:16, 11 August 2008
  • Pharmacology
    ... ling or [[metabolic pathway]]s by affecting sites directly on cell-surface receptors (which modulate and mediate cellular signaling pathways controlling cellul ...
    12 KB (1662 words) - 11:32, 20 August 2008
  • Immune System
    ... s also by bacteria. It can also attack cancer cells. The killer T cell has receptors that are used to search each cell that it meets. If a cell is infected, it ... The B lymphocyte cell searches for antigen matching its receptors. If it finds such antigen it connects to it, and inside the B cell a trigg ...
    6 KB (969 words) - 11:17, 11 August 2008
  • Diethylstilbestrol
    ... lic epoxidation, and the epoxide product has affinity towards the estrogen receptors.{{Fact|date=April 2007}} In some cases there are sons with only one testis ... ... lic epoxidation, and the epoxide product has affinity towards the estrogen receptors.[citation needed] In some cases there are sons with only one testis or bot ...
    34 KB (4923 words) - 11:19, 20 February 2009
  • Drug targets
    ... ation) or be the opposite of the endogenous substance which in the case of receptors is referred to as inverse agonism * G protein-coupled receptors
    7 KB (1041 words) - 05:38, 17 September 2008
  • Main Page
    ... ia/index.php/Category:HMRbase HMRbase] : A database of hormones and their receptors
    3 KB (489 words) - 03:44, 4 March 2011
  • Antibody
    ... of this antibody is normally very low as most IgE is tightly bound to its receptors on mast cells and basophils. The production of IgE is controlled by cytoki ... ... that will ultimately result in destruction of the invading microbe. The Fc receptors are isotype-specific, which gives greater flexibility to the immune system ...
    9 KB (1437 words) - 11:39, 18 August 2008
  • Antigens
    * Discrete sites on immunogens recognized by antibodies or T cell receptors
    2 KB (214 words) - 09:55, 18 August 2008
  • B Cells and T Cells
    ... L chains, VDJ rearranged on H chains. There is start of expression of IgM receptors. ... ent in the body; the B cell proliferates and secretes a free form of those receptors (antibodies) with identical binding sites as the ones on the original cell ...
    15 KB (2456 words) - 10:44, 18 August 2008
  • Bioinformatics Center, IMTECH
    ... Rsclass : A web tool for classification of amine type of G-protein coupled Receptors. Nucleic Acids Research 33:W143-7. 54. Bhasin, M. and Raghava, G. P. S. (2004) Classification of nuclear receptors based on amino acid composition and dipeptide composition. Journal of Biol ...
    34 KB (4785 words) - 10:18, 19 August 2008
  • PRRDB, pattern-recognition receptor
    ... information about innate immunity. It is a database of pattern recognition receptors and their ligands. The database is developed by Dr. Raghava's group at Bio ... ... prehensive database provides information about most of Pattern Recognition receptors and their ligands reported in literature. This information is essential as ...
    3 KB (407 words) - 04:15, 22 August 2008
  • TGN1412
    ... rage affinity this 'safe' dose (0.1 mg/kg) is sufficient to label all cd28 receptors available in the human body as can be easily deducted from simple antibody ...
    29 KB (4350 words) - 08:44, 22 August 2008
  • Ampligen
    ... receptors (or “TLRs”) such as TLR-3 serve as “pattern recognition” receptors in the early detection of pathogens and the establishment of early defense ... New research shows that these receptors present in virtually all life forms, from mosquitoes to man. In scientific ...
    20 KB (2874 words) - 11:26, 22 August 2008
  • Cimetidine
    ... , the SK&F scientists also proved the existence of histamine H<sub>2</sub>-receptors.
    8 KB (1141 words) - 05:03, 25 August 2008
  • Pharmacodynamics
    *[[Ligand binding]] to [[Receptor (biochemistry)|receptors]]: **[[Hormone]] receptors
    8 KB (1104 words) - 17:10, 29 August 2008
  • Drug interaction
    5 KB (686 words) - 10:34, 28 August 2008
  • Monoclonal antibodies
    ... onjugate or effector cell. In fact, every intact antibody can bind to cell receptors or other proteins with its Fc region.
    18 KB (2401 words) - 09:38, 1 September 2008
  • Dirty drug
    ... to describe [[drugs]] that may bind to many different molecular targets or receptors in the body, and so tend to have a wide range of effects and possibly nega ... ... ne]], [[dextromethorphan]] and [[ibogaine]], all of which bind to multiple receptors or influence multiple receptor systems. There may be instances of advanta ...
    2 KB (273 words) - 09:06, 17 September 2008

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