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- Protein subcellular localization prediction ... zation is an important component of [[bioinformatics]]-based prediction of protein function and [[genome project|genome annotation]], and it can aid the iden ... ... tions such as to a [[cell membrane]] or the [[extracellular]] environment. Proteins must be localized at their appropriate [[subcellular localization|subcell ...10 KB (1368 words) - 06:30, 20 August 2008
- Protein structure <script>select protein;ribbons on</script> ... n length is around 300 residues.Very large aggregates can be formed from [[protein subunit]]s, for example many thousand [[actin]] molecules assemble into a ...27 KB (4092 words) - 12:18, 4 December 2008
- Protein Structure Prediction ... having minimum free energy is considered as the native conformation of the protein. ... r such calculations are not good enough to model the native structure of a protein at atomic detail.3 KB (489 words) - 06:17, 18 August 2008
- List of protein structure prediction software ... ls in [[protein structure]] prediction, including [[homology modeling]], [[protein threading]], ''ab initio'' methods, secondary structure prediction, and tr ... | LIght Balance for Remote Analogous proteins, ver. I || Webserver || [http://libra.ddbj.nig.ac.jp/top-e.html server]7 KB (907 words) - 11:34, 18 August 2008
- Protein Data Bank ... at describes the 3D structures of molecules found in the Protein Data Bank|Protein Data Bank (file format)}} ... eased into the [[public domain]], and can be accessed for free. See also [[protein structure]].11 KB (1705 words) - 05:34, 19 August 2008
- Protein design ... tive native state. Protein design is a rational design technique used in [[protein engineering]]. ... which proteins [[protein folding|fold]]. In a sense it is the reverse of [[protein structure prediction|structure prediction]]: a [[tertiary structure]] is s ...5 KB (750 words) - 09:27, 26 August 2008
- Lattice protein ... simplified computer models of [[protein]]s which are used to investigate [[protein folding]]. ... l-atom detail. Hence real proteins cannot be folded on a computer. Lattice proteins, however, are simplified in two ways: the [[amino acid]]s are modelled as ...3 KB (481 words) - 09:52, 17 September 2008
- Protein-DNA interaction site predictor ... ructure- and sequence-based prediction of DNA-binding sites in DNA-binding proteins can be performed on several web servers listed below: ... es directly from amino acid sequence and hence is applicable for all known proteins. It is based on the chemical-physical properties of the residue and its e ...3 KB (426 words) - 06:12, 11 September 2008
- Protein-protein interaction '''Protein-protein interactions''' refer to the association of protein molecules and the study of these associations from the perspective of bioc ... ... they are phosphorylated on the amino acid tyrosine. In conclusion, protein-protein interactions are of central importance for virtually every process in a li ...12 KB (1655 words) - 09:01, 12 September 2008
- Putative uncharacterized protein nhr-259
334 B (27 words) - 05:37, 14 December 2009
- Protein F11A13b, confirmed by transcript evidence;DAF-12 A2
428 B (39 words) - 08:50, 14 December 2009
- Protein F11A13c, confirmed by transcript evidence;DAF-12 B
333 B (27 words) - 08:50, 14 December 2009
- Orphan nuclear receptor steroidogenic factor 1, SF-1(long terminal repeat-binding protein, ELP)
423 B (40 words) - 08:51, 14 December 2009
- Estrogen receptor protein (Estrogen receptor 1); Fragment
373 B (33 words) - 08:51, 14 December 2009
- FTZ-F1 related protein
471 B (45 words) - 08:51, 14 December 2009
- Protein H22D141, partially confirmed by transcript evidence
429 B (39 words) - 08:55, 14 December 2009
- Protein Y51A2D17, confirmed by transcript evidence
428 B (39 words) - 08:55, 14 December 2009
- Protein T03E63, confirmed by transcript evidence
427 B (39 words) - 08:56, 14 December 2009
- Protein F57G86, partially confirmed by transcript evidence
429 B (39 words) - 08:56, 14 December 2009
- Protein F09C69, confirmed by transcript evidence;Nuclear receptor NHR-116
429 B (39 words) - 08:56, 14 December 2009
Page text matches
- Targeted Drug Delivery ... by injection. For example, many immunizations are based on the delivery of protein drugs and are often done by injection. | Delivery of proteins and peptides for cancer therapy4 KB (602 words) - 13:27, 5 November 2011
- Drug Discovery o Proteins and enzymes * Some target classes, for example, the G-protein coupled receptors (GPCRs), have been successfully targeted, and a sizable ...23 KB (3467 words) - 03:48, 1 September 2008
- Dr. G. P. S. Raghava ... of Bioinformatics. His PhD work focuses on "Computer Aided Prediction of Protein Conformation from Amino Acid Sequences of Biotechnological Relevance" . ... e, where his primary duty is to built/maintain infrastructure required for protein modeling and engineering.14 KB (1994 words) - 12:53, 5 October 2008
- Target Identification ... discovery campaigns. These typically include newly discovered proteins, or proteins whose function has now become clear as a result of basic scientific resea ... ... on.Because a mutation in gene leads to change in structure and function of protein .Disease gene can be identified on the basis of hereditary patterns or com ...3 KB (452 words) - 06:49, 11 August 2008
- Virtual screening ... s to select a subset of compounds considered to be appropriate for a given protein target. Clearly, this strategy implies that some information is available ... ... either derived experimentally or from a model built by homology to related protein structures), and a docking code comprising an efficient searching algorith ...5 KB (724 words) - 06:29, 11 August 2008
- Docking ... e of two ways. The first approach uses the full scoring function to rank a protein-ligand conformation. The system is then modified by the search algorithm, ... *Protein-Protein Docking4 KB (593 words) - 04:42, 17 September 2008
- Molecular Mechanics ... .ncbi.nlm.nih.gov/pubmed/18514737 F. E. Boas and P. B. Harbury, "Design of protein-ligand binding based on the molecular-mechanics energy model," J. Mol. Bio ...8 KB (1146 words) - 08:33, 26 August 2008
- Target Validation '''Target validation''' involves proving that DNA, RNA or a protein molecule is directly involved in a disease process and can be a suitable t ... ... n of gene expression (gene knockdown, antisense, ribozymes and zinc finger proteins)865 B (117 words) - 17:29, 4 August 2008
- Homology Modeling '''Homology Modeling''' is a method of prediction of protein 3D structure from the amino acid sequence.This is also known as Comparativ ... ... large-scale experiment known as the Critical Assessment of Techniques for Protein Structure Prediction, or CASP.9 KB (1291 words) - 11:19, 19 August 2008
- Tuberculosis ... oteins predicted). Only 376 putative proteins share no homology with known proteins and thus could be unique to M. tuberculosis.7 KB (965 words) - 17:55, 30 September 2008
- Autoimmunity ... to severe thyroiditis that is due to immune recognintion of normal thyroid protein. Infection by organism including Epstein Barr virus or mycoplasma can prov ...2 KB (363 words) - 07:01, 11 August 2008
- Comparative Immunity walls, peptides and a protein that damages microbial membranes,1 KB (199 words) - 09:14, 11 August 2008
- RNAi therapeutics ... e of proteins, charge interactions and block the action of disease causing proteins. Developing a drug a time consuming process. Moreover, many molecules are ... ... ug for a particular protein due to lack of highly specific site within the protein. Such type of nondruggable target can be efficiently knockdown using RNAi ...3 KB (501 words) - 09:20, 11 August 2008
- Immune System ... s activated. Once activated, helper T cells start to divide and to produce proteins that activate B and T cells as well as other immune cells. ... and inside the B cell a triggering signal is set off. The B cell now needs proteins produced by helper T cells to become fully activated. When this happens, ...6 KB (969 words) - 11:17, 11 August 2008
- Ticrynafen ... 2C9 is the thiophene sulfoxide or the thiophene epoxide. The target on the protein is also not known (could be multiple). However tienilic acid is a good mec ...1 KB (204 words) - 09:43, 11 August 2008
- Drug targets ... et''' is frequently used in pharmaceutical research to describe the native protein in the body whose activity is modified by a drug resulting in a desirable ... * G protein-coupled receptors7 KB (1041 words) - 05:38, 17 September 2008
- Installing Bioperl for Unix DNA Smith-Waterman, {{PM|Bio::Tools::dpAlign}} for protein Smith-Waterman,17 KB (2842 words) - 10:16, 8 September 2008
- Protein subcellular localization prediction ... zation is an important component of [[bioinformatics]]-based prediction of protein function and [[genome project|genome annotation]], and it can aid the iden ... ... tions such as to a [[cell membrane]] or the [[extracellular]] environment. Proteins must be localized at their appropriate [[subcellular localization|subcell ...10 KB (1368 words) - 06:30, 20 August 2008
- CASP ... wide experiment (though it is commonly referred to as a competition) for [[protein structure prediction]] taking place every two years since 1994. ... for [[protein structure prediction]] from the [[primary structure]] of the protein. As a consequence, CASP provides the research community with an assessment ...3 KB (443 words) - 06:04, 27 August 2008
- Entrez ... s]], and references. The Entrez system can provide views of [[gene]] and [[protein]] sequences and [[chromosome]] maps. Some textbooks are also available onl ... *''Protein'': sequence database5 KB (692 words) - 04:33, 17 August 2008
