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- Phase II #Effect of the drug on metabolism.587 B (93 words) - 07:54, 31 July 2008
- ADMET '''ADMET''' absorption, distribution, metabolism, excretion and toxicology, describes the disposition of a pharmaceutical ... ... t), distribution determines if the drug can arrive at the place of action, metabolism determines whether the drug is broken down before it can arrive at place o ...3 KB (515 words) - 12:01, 29 August 2008
- Toxicology ... of which may be reversible or irreversible, include absorption, transport, metabolism to more or less toxic metabolites, excretion, interaction with cellular ma ... * Metabolism5 KB (751 words) - 08:13, 19 August 2008
- RNAi therapeutics (4) Distribution and metabolism: These drugs are very similar from drug to drug, resulting in a common and ...3 KB (501 words) - 09:20, 11 August 2008
- Pharmacology ... ing neuropharmacology, renal pharmacology, human metabolism, intracellular metabolism, and intracellular regulation.]] * [[Drug metabolism|Metabolism]] - Is the medication converted chemically inside the body, and into which ...12 KB (1662 words) - 11:32, 20 August 2008
- Diethylstilbestrol | metabolism = Hepatic34 KB (4923 words) - 11:19, 20 February 2009
- Ticrynafen ... act as a suicide substrate at the cytochrome P450 enzymes involved in drug metabolism. Unfortunately, the metabolic reaction carried out by these enzymes conver ...1 KB (204 words) - 09:43, 11 August 2008
- Mechanistic Toxicology * Chemistry, often xenobiotic metabolism656 B (81 words) - 10:03, 11 August 2008
- Drug targets ... on of specific genes thereby controlling the development, homeostasis, and metabolism of the organism.7 KB (1041 words) - 05:38, 17 September 2008
- Pharmacokinetics ... ding, but not limited to, the extent and rate of Absorption, Distribution, Metabolism and Excretion. This sometimes is referred to as the [[ADMET|ADME]] scheme.280 B (44 words) - 07:11, 18 August 2008
- DNA ... by DOI bot-->}}</ref> RNA may have acted as the central part of early cell metabolism as it can both transmit genetic information and carry out [[catalysis]] as ...82 KB (11827 words) - 06:08, 20 August 2008
- Systems biology ... , the group of Masaru Tomita published the first quantitative model of the metabolism of a whole (hypothetical) cell.18 KB (2525 words) - 05:00, 12 September 2008
- Pharmacogenetics ... evel of pharmacogenetics, involving variation in genes involved in, [[drug metabolism]] with a particular emphasis on improving drug safety. The wider use of ph ... ... , the [[cytochrome P450 oxidase]]s (CYP450) are heavily involved in [[drug metabolism]], and genetic variations in CYP450s affect large populations. One member ...7 KB (983 words) - 05:45, 21 August 2008
- Ampligen | metabolism =20 KB (2874 words) - 11:26, 22 August 2008
- Cimetidine | metabolism = [[Liver|Hepatic]] ... h as those used in [[hormonal contraception]]. Cimetidine interferes with metabolism of the hormone [[estrogen]], enhancing estrogen activity. In women, this c ...8 KB (1141 words) - 05:03, 25 August 2008
- BIAdb Berberine 1438 | metabolism =2 KB (244 words) - 08:26, 10 December 2009
- Dorzolamide | metabolism =3 KB (429 words) - 05:08, 25 August 2008
- Prodrug ... ale behind the use of a prodrug is generally for absorption, distribution, metabolism, and excretion ([[ADME]]) optimization. Prodrugs are usually designed to i ... ... overies, and the drug is only identified as a prodrug after extensive drug metabolism studies. Some prodrugs, such as [[Codeine]] and [[Psilocybin]], also occur ...5 KB (640 words) - 06:41, 25 August 2008
- Zidovudine | bioavailability = near complete absoprtion, following first-pass metabolism systemic availability 65% (range 52 to 75%) | metabolism = [[Liver|Hepatic]]16 KB (2364 words) - 06:44, 25 August 2008
- Metabonomics Metabolites are the intermediates and products of [[metabolism]]. The term ''metabolite'' is usually restricted to small [[molecule]]s. A ... ... erprint, which reflects the balance of all these forces on an individual's metabolism.<ref> [http://www.nugo.org/everyone The European Nutrigenomics Network]</r ...25 KB (3638 words) - 04:58, 26 August 2008