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- Metabolic Network ... athways can exist within a cell. This collection of pathways is called the metabolic network. Pathways are important to the maintenance of homeostasis within a ... A metabolic network is the complete set of metabolic and physical processes that determine the physiological and biochemical pr ...1 KB (211 words) - 03:56, 19 September 2008
- Analysis of Metabolic ‘Choke’ and ‘Load’ points as Drug Targets in Pathogenic Bacteria == '''Analysis of Metabolic ‘Choke’ and ‘Load’ points as Drug Targets in Pathogenic Bacteria'' ... ... any human pathogens thus necessitates a renewed vigor in the assessment of metabolic networks and its capabilities towards identification of drug targets.3 KB (480 words) - 12:38, 27 September 2008
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- Pharmacology ... eptors]], to design chemicals that act on specific cellular signaling or [[metabolic pathway]]s by affecting sites directly on cell-surface receptors (which mo ...12 KB (1662 words) - 11:32, 20 August 2008
- Diethylstilbestrol ... ilbestrol can also cause feminisation of the male foetus, as DES undergoes metabolic epoxidation, and the epoxide product has affinity towards the estrogen rec ... ... ilbestrol can also cause feminisation of the male foetus, as DES undergoes metabolic epoxidation, and the epoxide product has affinity towards the estrogen rec ...34 KB (4923 words) - 11:19, 20 February 2009
- Ticrynafen ... he cytochrome P450 enzymes involved in drug metabolism. Unfortunately, the metabolic reaction carried out by these enzymes converted tienilic acid to a thiophe ...1 KB (204 words) - 09:43, 11 August 2008
- Mechanistic Toxicology Chemical research in [[toxicology]] usually investigates metabolic transformations of drugs or potentially hazardous chemicals. * Are [[metabolic]] products toxic?656 B (81 words) - 10:03, 11 August 2008
- Drug targets ... ong many possibilities, the set of enzymes made in a cell determines which metabolic pathways occur in that cell.7 KB (1041 words) - 05:38, 17 September 2008
- QSAR ... tablish the level of inhibition of particular [[signal transduction]] or [[metabolic pathways]]. Chemicals can also be biologically active by being toxicity. [ ...6 KB (859 words) - 09:16, 20 August 2008
- Enzyme ... eight compounds,proteineous nature, biological molecules that take part in metabolic pathways by either accerlating or inhibiting a particular reaction.Enzymes ...336 B (48 words) - 06:09, 18 August 2008
- Systems biology ... and behavior of that system (for example, the enzymes and metabolites in a metabolic pathway). ... ment of several approaches to study complex molecular systems, such as the Metabolic Control Analysis and the biochemical systems theory. The successes of mole ...18 KB (2525 words) - 05:00, 12 September 2008
- Proprint ... ns such as enzyme catalysis, ligand receptor binding, signal transduction, metabolic pathway, regulatory processes etc. In the present study we demonstrated th ...2 KB (284 words) - 10:22, 19 August 2008
- Proteomics ... f living organisms, as they are the main components of the physiological [[metabolic pathways]] of [[biological cell|cells]]. The term "proteomics" was coined ... ... Valkova N, et al. "Pathway Analysis of Kidney Cancer Using Proteomics and *Metabolic Profiling." Biomed Central: 65-82, (24 November 2006).16 KB (2303 words) - 09:50, 17 September 2008
- Drug design ... a key [[molecule]] involved in a particular [[metabolic]] or signalling [[Metabolic pathway|pathway]] that is specific to a disease condition or [[pathology]] ...6 KB (827 words) - 06:06, 17 September 2008
- Prodrug ... nowledge of chemical properties likely to improve absorption and the major metabolic pathways in the body allows the modification of the structure of new chemi ... | Type I || Intracellular || Type IB || Metabolic tissues (liver/lung etc) || [[Captopril]], [[Cyclophosphamide]]5 KB (640 words) - 06:41, 25 August 2008
- Metabonomics ... analyses do not tell the whole story of what might be happening in a cell, metabolic profiling can give an instantaneous snapshot of the physiology of that cel ... ... tabolome refers to the complete set of small-molecule metabolites (such as metabolic intermediates, hormones and other signalling molecules, and secondary meta ...25 KB (3638 words) - 04:58, 26 August 2008
- Pharmacodynamics ... d concentrations cannot be maintained with absolute consistency because of metabolic breakdown and excretory clearance. [[Genetics|Genetic]] factors may exist ... *Interaction (additive, multiplicative, or metabolic)8 KB (1104 words) - 17:10, 29 August 2008
- Drug interaction ==Metabolic drug interactions== One notable system involved in metabolic drug interactions is the enzyme system comprising the [[cytochrome P450 ox ...5 KB (686 words) - 10:34, 28 August 2008
- Drug discovery hit to lead ... s with improved potency, reduced off-target activities, and physiochemical/metabolic properties suggestive of reasonable in vivo [[pharmacokinetics]]. This opt ...4 KB (541 words) - 06:08, 17 September 2008
- Drug resistance ==Metabolic price== ''Biological cost'' or ''[[metabolic price]]'' is a measure of the increased [[energy metabolism]] required to ...5 KB (674 words) - 10:32, 1 September 2008
- Ayurveda ... ystem. Pitta is the principle of biotransformation and is the cause of all metabolic processes in the body. Kapha is the principle of cohesion and functions th ... ... ''Malas''' : These are the waste materials produced as a result of various metabolic activities in the body. The three main waste products are urine, faeces an ...20 KB (3217 words) - 03:40, 2 September 2008
- Off-licenced drug ... [[medication|medicine]] but is used to treat a rare condition (e.g. a rare metabolic disease).2 KB (313 words) - 03:56, 2 September 2008
- Epigenetics ... n patterns have most frequently been seen in cancer and some other special metabolic states847 B (131 words) - 19:31, 3 September 2008
