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  • Homology Modeling
    ... accuracy, especially on protein types underrepresented in the PDB, such as membrane proteins.
    9 KB (1291 words) - 11:19, 19 August 2008
  • Tuberculosis
    Mycobacteria are weakly Gram-positive (no outer cell membrane), non-motile, pleomorphic rods, related to the Actinomyces. Most Mycobacte ... ... such as the upper lobes of lungs, kidneys, bone marrow, and meninges—the membrane like coverings of brain and spinal cord.
    7 KB (965 words) - 17:55, 30 September 2008
  • Protein subcellular localization prediction
    ... cytoplasm and some must be targeted to other locations such as to a [[cell membrane]] or the [[extracellular]] environment. Proteins must be localized at thei ... ... [drug discovery]] process. For example, [[secreted protein]]s and [[plasma membrane]] proteins are easily accessible by drug molecules due to their localizati ...
    10 KB (1368 words) - 06:30, 20 August 2008
  • Antibody
    ... must bind through the membrane. Surface IgM binds directly as an integral membrane protein, it does not bind to an IgM Fc receptor like IgE does. ... the complement cascade. Secondly, some complement system components form a membrane attack complex to assist antibodies to kill the bacterium directly.
    9 KB (1437 words) - 11:39, 18 August 2008
  • B Cells and T Cells
    ... recognize free (soluble) antigen in the blood or lymph using their BCR or membrane bound-immunoglobulin. In contrast, T cells recognize their cognate antigen ... ... vating the transcription factors NF-κB and AP-1. IP3 is released from the membrane by PLCγ and diffuses rapidly to activate receptors on the ER, which induc ...
    15 KB (2456 words) - 10:44, 18 August 2008
  • IMTECH
    '''France :''' on projects "Cloning and functional analysis of plasma membrane glutathione transporters in yeasts and plants" and "Role of glutathione tr ...
    15 KB (2164 words) - 09:50, 19 August 2008
  • TBpred
    ... four subcellular localization (cytoplasmic,integral membrane,secretory and membrane attached by lipid anchor) of <b>mycobacterial proteins</b>.It is SVM based ... <tr><td>2.Integral Membrane</td><td>402</td></tr>
    7 KB (1080 words) - 16:48, 31 August 2008
  • HSLpred
    ... jor subcellular localization (cytoplasm, mitochondrial, nuclear and plasma membrane) of human proteins. ... man proteins (840 cytoplasmic, 315 mitochondrial, 858 nuclear, 1519 plasma membrane). The dataset is available at www.imtech.res.in/raghava/hslpred
    4 KB (618 words) - 08:45, 20 August 2008
  • "druglikeness"
    ... embrane to reach the inside of a cell. The model compound for the cellular membrane is [[octanol]], so the logarithm of the octanol/water [[partition coeffici ...
    2 KB (320 words) - 07:11, 8 September 2008
  • PRRDB, pattern-recognition receptor
    ... further classified as single-pass type I/II membrane proteins, multi-pass membrane proteins, cytoplasmic or secreted proteins depending upon their site of ex ...
    3 KB (407 words) - 04:15, 22 August 2008
  • TGN1412
    ... syndrome]] resulting in [[angioedema]], swelling of [[skin]] and [[mucous membrane]]s, akin to the effects of the complement cascade in severe allergic react ...
    29 KB (4350 words) - 08:44, 22 August 2008
  • Zidovudine
    ... up increases the [[lipophilic]] nature of AZT, allowing it to cross [[cell membrane]]s easily by [[diffusion]] and thereby also to cross the [[blood-brain bar ...
    16 KB (2364 words) - 06:44, 25 August 2008
  • Molecul;ar Modelling
    ... omolecular function]], and molecular recognition of proteins, [[DNA]], and membrane complexes.
    8 KB (1088 words) - 09:16, 1 September 2008
  • Malaria vaccine
    ... in synthesis. The proteins then produced are expressed on the cell surface membrane of the ‘infected’ cell. These bind to the [[HLA molecules]], priming T ...
    26 KB (3922 words) - 11:25, 25 August 2008
  • Biological Target
    ... in synthesis. The proteins then produced are expressed on the cell surface membrane of the ‘infected’ cell. These bind to the [[HLA molecules]], priming T ...
    26 KB (3922 words) - 11:27, 25 August 2008
  • HB plot
    ... . '''The [[cytochrome P450]]s (P450s)''' are [[xenobiotic]]-metabolizing [[membrane]]-bound [[heme]]-containing enzymes that use molecular [[oxygen]] and elec ...
    8 KB (1156 words) - 09:51, 17 September 2008
  • PSLpred
    ... ve bacteria) have 5 major subcellular localizations (outer membrane, inner membrane, periplasm, cytoplasm, and extracellular), specialized in distinct biochem ... ... proteins (248 cytoplasmic, 268 inner membrane, 244 periplasmic, 352 outher membrane, and 190 extracellular) having single subcellular localization were used f ...
    6 KB (896 words) - 07:07, 27 August 2008
  • Pharmacodynamics
    *[[Cellular membrane]] disruption ... [General anesthetic]]s were once thought to work by disordering the neural membranes, thereby altering the Na<sup>+</sup> influx. [[Antacid]]s and [[chelating ...
    8 KB (1104 words) - 17:10, 29 August 2008
  • Diphtheria
    ... characterized by sore throat, low fever, and an adherent membrane (a pseudomembrane) on the tonsils, pharynx, and/or nasal cavity. A milder form of diphtheria ... * An adherent pseudomembrane of the tonsil(s), pharynx, and/or nose.
    6 KB (894 words) - 04:23, 1 September 2008
  • Leprosy
    ... symptoms of leprosy vary but primarily affect the skin, nerves, and mucous membranes. Patients with this chronic infectious disease are classified as having p ... ... 'M. leprae'' is aerobic and rod-shaped, and is surrounded by the waxy cell membrane coating characteristic of Mycobacterium species.
    16 KB (2476 words) - 04:23, 1 September 2008

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