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• Nonribosomal peptide
  ... glycosylated]], [[Acylation|acylated]], [[Halogenation|halogenated]], or [[Hydroxylation|hydroxylated]]. Cyclization of amino acids against the peptide "backbone" ... ... odified, e.g., by [[glycosylation]], [[acylation]], [[halogenation]], or [[hydroxylation]]. The responsible enzymes are usually associated to the synthetase comple ...
  9 KB (1134 words) - 09:44, 17 September 2008
• Ethinyl Estradiol
  ... ly bound to [[human serum albumin|plasma albumin]]. It is metabolized by [[hydroxylation]] of the aromatic ring and excreted in both, feces and urine, in part as ...
  12 KB (1540 words) - 09:12, 24 February 2009
• Calcitriol
  ... ves 24-hydroxylase to produce calcitroic acid; the second pathway involves hydroxylation and cyclization. Calcitrol also undergoes enterohepatic recycling.
  10 KB (1301 words) - 05:53, 20 February 2009
• Pregnenolone
  ... regnenolone is synthesized from [[cholesterol]]. This conversion involves hydroxylation at the [[side-chain]] at C20 and C22 positions, with cleavage of the side- ...
  5 KB (687 words) - 09:34, 19 February 2009
• Aldosterone
  ... . These enzymes are nearly identical (they share 11β-hydroxylation and 18-hydroxylation functions). But aldosterone synthase is also able to perform a 18-oxidatio ...
  17 KB (2332 words) - 11:48, 19 February 2009
• Serotonin
  ... ated]] by [[tryptophan decarboxylase]] to give tryptamine, which is then [[Hydroxylation|hydroxylated]] by the [[cytochrome P450 monooxygenase]], [[tryptamine 5-hy ...
  38 KB (5178 words) - 12:28, 19 February 2009
• 17-Hydroxypregnenolone
  ... ''17α-hydroxypregnenolone'''), is a C21 [[steroid]] that is obtained by [[hydroxylation]] of [[pregnenolone]] at the C17α position. This step is performed by th ...
  5 KB (643 words) - 11:24, 19 February 2009
• Dydrogesterone
  ... of oestrogenic effects. Furthermore, dydrogesterone does not undergo 17α-hydroxylation, which explains its lack of androgenic effects.
  13 KB (1840 words) - 03:54, 24 February 2009
• 7-a,25-Dihydroxycholesterol
  ... ell line MDA-231 did not express 7 alpha-hydroxylase activity. The 7 alpha-hydroxylation of 25-hydroxycholesterol in HDF could be stimulated by dexamethasone and c ...
  2 KB (324 words) - 05:33, 11 December 2009
• Parathyroid hormone (Parathyrin) (PTH)
  ... roxyvitamin D3 1-alpha-hydroxylase]], the enzyme responsible for 1-alpha [[hydroxylation]] of [[25-hydroxy vitamin D]], converting vitamin D to its active form ([[ ...
  12 KB (1604 words) - 08:15, 17 February 2009

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