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  • Targeted Drug Delivery
    ... ns such as peptide and protein, antibody, vaccine and gene based drugs, in general may not be delivered using these routes because they might be susceptib ... | Gene therapy
    4 KB (602 words) - 13:27, 5 November 2011
  • Drug Discovery
    ... activity ,use cheminformatics software like Chemdraw ,Hyperchem that will generate the structure of molecule and this reduce the time and money in drug d ... o Defects in distinct genes—genetic disorders
    23 KB (3467 words) - 03:48, 1 September 2008
  • Dr. G. P. S. Raghava
    ... ge VaxiPred: Computer aided vaccine design, which was launched by Director General, CSIR Dr R A Mashlekar on 15th of December 2004. *Member of Editorial Advisory Board of journal Recent Patents on DNA & Gene Sequences
    14 KB (1994 words) - 12:53, 5 October 2008
  • Target Identification
    ... of identifying the molecule where a drug molecule can bind.eg. enzyme etc.Generallythe target molecule is can be two types. ... pathology. The more such information is available, the less investment is (generally) required to develop a therapeutic directed against the target.
    3 KB (452 words) - 06:49, 11 August 2008
  • Target Validation
    ... essful drug target validation in vitro is the ability to knock-down target gene expression effectively and with high specificity. *downregulation of gene expression (gene knockdown, antisense, ribozymes and zinc finger proteins)
    865 B (117 words) - 17:29, 4 August 2008
  • RNAi therapeutics
    ... ered by double stranded RNA (dsRNA). The enzyme Dicer process the dsRNA to generate 20-25 bp fragments and one of the two strand bind to the RISC (RNA-ind ... ... athway is also a promising tool in medicine to shut down a disease-causing gene.
    3 KB (501 words) - 09:20, 11 August 2008
  • Drug targets
    ... work in concert with other proteins to regulate the expression of specific genes thereby controlling the development, homeostasis, and metabolism of the o ... ... eceptor which in turn activates the receptor resulting in up-regulation of gene expression.
    7 KB (1041 words) - 05:38, 17 September 2008
  • Indipedia: India's Wikipedia at OSDD:Current events
    ... ene wiki" to collect information on the relationship and function of human genes. See also the description from the PLoS press release
    2 KB (378 words) - 19:20, 15 August 2008
  • Entrez
    ... ure|structures]], and references. The Entrez system can provide views of [[gene]] and [[protein]] sequences and [[chromosome]] maps. Some textbooks are al ... *''Gene'': gene-centered information
    5 KB (692 words) - 04:33, 17 August 2008
  • Protein structure
    ... generally not stable by themselves, since the water-amide hydrogen bond is generally more favorable than the amide-amide hydrogen bond. Thus, secondary s ... ... lfide bonds are extremely rare in cytosolic proteins, since the cytosol is generally a reducing environment.
    27 KB (4092 words) - 12:18, 4 December 2008
  • Protein Structure Prediction
    ... ources like those afforded by either powerful supercomputers (such as Blue Gene or MDGRAPE-3) or distributed computing (such as Folding@home, the Human Pr ...
    3 KB (489 words) - 06:17, 18 August 2008
  • Genomics
    ... ne location, the length and number of coding regions (called exons) within genes, the amount of noncoding DNA in each genome, and highly conserved regions ... ! style="background:brown; color:white" |estimatedgene number average
    5 KB (708 words) - 07:03, 18 August 2008
  • B Cells and T Cells
    ... sed of two identical light (L) and two identical heavy (H) chains, and the genes specifying them are found in the 'V' (Variable) region and the 'C' (Const ... * Progenitor B cells - Contains Germline H genes, Germline L genes
    15 KB (2456 words) - 10:44, 18 August 2008
  • Drugs in clinical trial
    |Nerve Growth Factor Gene Therapy
    3 KB (438 words) - 05:53, 21 August 2008
  • DNA
    {{for|a non-technical introduction to the topic|Introduction to genetics}} ... es have structural purposes, or are involved in regulating the use of this genetic information.
    82 KB (11827 words) - 06:08, 20 August 2008
  • Vaccine
    ... sFlu.jpg‎|thumbnail|300px|[[Avian Flu]] vaccine development by [[reverse genetics]] techniques.]] ... lled ''DNA vaccination'', has been developed. It works by insertion (and [[Gene expression|expression]], triggering immune system recognition) into human ...
    21 KB (3042 words) - 07:01, 19 August 2008
  • Synthetic biology
    ... logy where not only existing genes are described and analyzed but also new gene arrangements can be constructed and evaluated. ''Nevertheless, the term wa ... ... query_hl=2 ] is one good example of such work. Elowitz had a model for how gene expression should work inside living cells. To test his model, he built a ...
    17 KB (2568 words) - 06:47, 17 September 2008
  • Systems biology
    ... seen as a precursor of systems biology is Ludwig von Bertalanffy with his general systems theory. One of the first numerical simulations in biology was p ... ... ssue gene expression measurements by DNA microarrays or serial analysis of gene expression
    18 KB (2525 words) - 05:00, 12 September 2008
  • IMTECH
    * Molecular Biology and Microbial Genetics ... established and newly emerging areas of relevant biotechnology including genetic engineering.
    15 KB (2164 words) - 09:50, 19 August 2008
  • Bioinformatics Center, IMTECH
    ... allenge for bioinformaticians to annotate these genomes for predicting the genes and the repeat regions. A few web servers in this area have been develope ... ... und:beige;text-align:center"|[http://www.imtech.res.in/raghava/svmgene/ SVMgene]
    34 KB (4785 words) - 10:18, 19 August 2008

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