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- Drug Discovery ... lelic variants can increase susceptibility for diseases, such as the ApoE4 allele does for Alzheimer's. ... eutics. For example, this approach is being investigated to silence mutant alleles of tau, APP, ataxin, and SOD1.23 KB (3467 words) - 03:48, 1 September 2008
- Pharmacogenetics ... affected people, this deficiency results from one of three common variant alleles. ... ponse to treatment, which raises whether people who have two [[wild-type]] alleles could tolerate a higher therapeutic dose.7 KB (983 words) - 05:45, 21 August 2008
- Malaria vaccine e) Does the antigen contain epitopes that are recognisable by HLA allele superfamilies?26 KB (3922 words) - 11:25, 25 August 2008
- Biological Target e) Does the antigen contain epitopes that are recognisable by HLA allele superfamilies?26 KB (3922 words) - 11:27, 25 August 2008
- Abacavir ... estern countries. There is a strong relationship with race: the [[HLA-B57#Allele_distribution|prevalence of ''HLA-B*5701'']] in India is 20–50%, but ... ... *5701 are available and all patients should be screened for the HLA-B*5701 allele before starting or restarting treatment with abacavir or abacavir containi ...7 KB (1000 words) - 03:50, 27 August 2008
- Adverse drug reaction Inheriting abnormal [[allele]]s of [[cytochrome]] [[cytochrome P450|P450]] can alter drug metabolism. T ... ... [cytochrome]] [[cytochrome P450|P450]] due to either inheriting abnormal [[allele]]s or due to drug interactions. Tables are available to check for drug int ...10 KB (1362 words) - 09:55, 28 August 2008
- Gregor Mendel ... contain only one gene of the pair. Offspring therefore inherit one genetic allele from each parent when sex cells unite in fertilization.1 KB (236 words) - 17:01, 31 August 2008
- Datasets in Bioinformatics ... s-I binding regions in antigens. It implements matrices for 47 MHC Class-I alleles, proteasomal and immunoproteasomal models. The main aim of this server is ... ... assification from 97 to 99% was obtained with HLA-DR1, HLA-DR2 and HLA-DR5 allele. This is the highest accuracy reported by any method. The prediction metho ...16 KB (2424 words) - 11:41, 5 September 2008
- SNP ... there are two ''alleles'' : C and T. Almost all common SNPs have only two alleles. ... pulation, SNPs can be assigned a minor allele frequency — the lowest allele frequency at a locus that is observed in a particular population.6 KB (930 words) - 08:53, 16 September 2008
- Phenytoin ... a particular human leukocyte antigen-B (HLA-B) allele, HLA-B*1502.[7] This allele occurs almost exclusively in patients with ancestry across broad areas of ... ... Man CB, Kwan P, Baum L, et al (May 2007). "Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese". Epilep ...9 KB (1359 words) - 04:42, 15 October 2008
- Insulin B chain === Alleles === A variety of mutant [[allele]]s with changes in the coding region have been identified. There is a read ...41 KB (5927 words) - 06:25, 18 February 2009
- Guideline for creating Immunotation of Mtb ... e 'Sorted Binding Regions' links and now copy the whole page starting from ALLELE Table, paste in word pad or notepad.<br> ... ng.html IEDB] paste the sequence in raw format, select All alleles in 'MHC allele' field, select Total score in 'Sort peptides by' field, then submit and f ...7 KB (1131 words) - 06:11, 15 January 2010
