Somatostatin receptor type 3

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Source Organism 2 Taxomomy 3 Subcellular Localization 4 Developmental Stage 5 Similarity 6 Post translational Modification 7 Function

[edit] Source Organism

Mus musculus (Mouse).

[edit] Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.

[edit] Subcellular Localization

Cell membrane; multi-pass membrane protein (By similarity). Note=Internalized into endoplasmic vesicles upon somatostatin-stimulation (By similarity).

[edit] Developmental Stage

[edit] Similarity

Belongs to the G-protein coupled receptor 1 family.

[edit] Post translational Modification

Phosphorylated. Phosphorylation increases upon somatostatin binding (By similarity).

[edit] Function

Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase.