Salmonella typhimurium
From DrugPedia: A Wikipedia for Drug discovery
Salmonella typhimurium
A rod-shaped Gram-negative enterobacteria; cause typhoid fever and food poisoning; can be used as a bioweapon.
| Kingdom | Bacteria |
|---|---|
| Class | Gamma Proteobacteria |
| Order | Enterobacteriales |
| Family | Enterobacteriaceae |
| Genus | Salmonella |
| Species | S. typhimurium |
| Binomial | Salmonella typhimurium |
Contents |
[edit] Surface Characteristics
LPS is composed of three parts: (1) lipid A, (2) core polysaccharide, and (3) O antigen. The lipid A region contains two glucosamine sugar derivatives, each with three fatty acids and phosphate or pyrophosphate attached. The core polysaccharide has KDO and attached to lipid A. The side chain O is small polysaccharide chain extending outward from the core, it has several peculiar sugars and varies in composition between bacterial strains.
[edit] Transmission
Salmonella infections are zoonotic and can be transferred between humans and nonhuman animals. Many infections are due to ingestion of contaminated food.
[edit] Pathogenic Activity
S. Typhimurium, causes a wide range of infections in birds and mammals, ranging from self-limiting gastroenteritis to severe systemic paratyphoid diseases; conveyed by contaminated foodstuffs; causes Salmonella enteritis (food poisoning) in humans.
