Prostaglandin D2

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Show 3-D Structure

Prostaglandin D2
Systematic (IUPAC) name
(Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid
Identifiers
CAS number	41598-07-6
ATC code	?
PubChem	448457
DrugBank	DB02056
Chemical data
Formula	C20H32O5
Mol. mass	352.47
SMILES	eMolecules & PubChem
Synonyms	PGD2
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.

[edit] General Properties

*Molecular Weight

352.47

*Molecular Formula

C₂₀H₃₂O₅

*IUPAC NAME

(Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxocyclopentyl]hept-5-enoic acid

*Canonical Smiles

CCCCCC(C=CC1C(C(CC1=O)O)CC=CCCCC(=O)O)O

*Isomeric Smiles

CCCCC[C@@H](C=C[C@@H]1[C@H]([C@H](CC1=O)O)CC=C/CCCC(=O)O)O

[edit] PhysioChemical Properties

*Melting Point

*LogP

*Water Solubility

[edit] External Links

• [1]Pubchem
• [2]]1RY0,
• [3]KEGG Compound
• [4]Human Metabolome DataBase
• [5]Drugbank