PolysacDB Phenolic glycolipid TB antigen 1743
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Phenolic glycolipid TB antigen
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Mycobacterium tuberculosis canetti
[edit] Basic Structure
Phenolic glycolipid consist of phenol phthiocerol as a common structure and a carbohydrate determinant that consists of 2,3,4-Me3Fuc-Rha-2-O-MeRha residues
[edit] Proposed functions
It has been widely used for the serodiagnosis of leprosy and has been implicated in the pathogenesis of leprosy
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab III604
[edit] Antibody type and class
IgG3
[edit] Assay System
ELISA and dot ELISA
[edit] Cross-reactivity
This Mab was specific to M. tuberculosis phenolic glycolipid and did not cross-react with other phenolic glycolipids from Mycobacterium leprae, M. bovis, and M. kansasii
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This Mab may be useful as a diagnostic reagent
