PolysacDB Peptide mimotope 1761
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Peptide mimotope
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Mycobacterium tuberculosis
[edit] Basic Structure
The peptide consisted of the following sequence : QEPLMGTVPIRAGGGS
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Purified peptide
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Polysera
[edit] Antibody type and class
N/A
[edit] Assay System
ELISA, immunoblotting
[edit] Cross-reactivity
This antisera recognized mannosylated Mycobacterium tuberculosis cell-wall antigens arabinomannan, lipoarabinomannan and the glycosylated recombinant protein Apa. The antisera also cross-reacted with mannans from Saccharomyces cerevisiae, but did not react with phosphatidyl-inositol-di-mannoside or arabinogalactan from Mycobacteria
[edit] Proposed epitopes
The epitope was proposed to be oligomannosidic in nature
[edit] Proposed Utility
This peptide mimotope can used as surrogate reagent for immunodiagnosis of tuberculosis
