PolysacDB O-polysaccharide 2063
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
O-polysaccharide
[edit] Carbohydrate Class
O-polysaccharide [LPS]
[edit] Source Microbe
Pseudomonas syringae serogroup O1 strain helianthi CFBP 2149
[edit] Basic Structure
O-polysaccharides of the LPS consists of tetra- and tri-α-D-rhamnose repeats in the backbone [-3)D-Rha(α1->3)D-Rha(α1-->2)D-Rha(α1->2)D-Rha(α1] and [3)D-Rha(α1-->3)D-Rha(α1-->2)D-Rha(α1-]
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab Ps(1-2)a1
[edit] Antibody type and class
IgG1
[edit] Assay System
ELISA, agglutination and immunoblotting
[edit] Cross-reactivity
"This Mab cross-reacts with chemotypes 1B, 1C-1A, 2A, and 2D-2A but not with those of chemotypes 1C, 1D, 1D-1A, and 2D"
[edit] Proposed epitopes
MAb Ps(1-->2)α1 is specific to a region of the linkage between the OPS and the LPS core, which is suggested to be the same in all P. syringae O1 and O2 LPSs
[edit] Proposed Utility
This Mab agglutinated heat-killed homologous bacterial cells
