PolysacDB Mannan 1352

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Mannan

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Candida albicans serotype A

[edit] Basic Structure

An α-linked branched homopolymer of mannose linked to protein

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

heat-killed cell suspension of C. albicans M1012(serotype A)

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab CA5-4

[edit] Antibody type and class

IgM

[edit] Assay System

Slide agglutination tests, immunofluorescence

[edit] Cross-reactivity

This Mab cross-reacted with C. albicans serotype B, and C. tropicalis strains

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab had agglutinating properties and may be useful also as reagents for revealing the immunochemical structures of specific determinants of C. albicans cell wall mannans

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database