PolysacDB Lipopolysaccharide 2566
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Xanthomonas hyacinthi S148
[edit] Basic Structure
The Xanthomonas LPS showed a predominance of mannose (Man), glucose (Glc), galacturonic acid (GalA), and N-acetylglucosamine (GlcNAc) residues
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
crude cell wall preparation and purified fimbriae
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab 3E10
[edit] Antibody type and class
IgG3
[edit] Assay System
immunoblotting, immunofluorescence, enzyme-linked immunosorbent assay (ELISA), and immunoelectron microscopy
[edit] Cross-reactivity
This Mab cross-reacted with all X. hyacinthi strains. No cross-reaction was found with 27 other Xanthomonas pathovars tested or with 14 other bacterial species from other genera, such as Erwinia and Pseudomonas
[edit] Proposed epitopes
The O antigen was found to consist of rhamnose and fucose in a 2:1 molar ratio. This Mab recognized both R-LPS and S-LPS
[edit] Proposed Utility
This Mab could be useful for structural studies, for detection purposes in commercial and agricultural settings, and for serological typing purposes
