PolysacDB Lipopolysaccharide 2206
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Serogroup D Salmonella
[edit] Basic Structure
LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part of Salmonella enterica group D LPS is as follows : -2)-α-D-Manp [branched to α-Tyvp-(1-->3)] -(1-->4)-α-L-Rhap-(1-->3)-α-D-Galp [branched to α-D-Glcp-(1-->4)]-(1-
[edit] Proposed functions
LPS plays an important virulence role based on its antiphagocytic and endotoxic properties
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab SA:5D12A
[edit] Antibody type and class
N/A
[edit] Assay System
ELISA
[edit] Cross-reactivity
This Mab reacted with Salmonella serogroups A-E and a rough strain of S. cholerae-suis
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
The usefulness of Mabs can be generated for diagnostic and protective purposes
