PolysacDB Lipopolysaccharide 2170
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Salmonella typhimurium
[edit] Basic Structure
LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen part consists of the following residues : -2)-α-D-Manp [branched to α-Abep-(1-->3)] -(1-->4)-α-L-Rhap-(1-->3)-α-D-Galp-(1-
[edit] Proposed functions
LPS plays an important virulence role based on its antiphagocytic and endotoxic properties
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab MO4-3
[edit] Antibody type and class
IgG3
[edit] Assay System
ELISA, immunoblotting
[edit] Cross-reactivity
This Mab was also specific but cross-reacted with Salmonella paratyphi serogroup A
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This Mab can be used as a serotyping reagent for the identification of serogroup B salmonellae in a routine diagnostic bacteriology laboratory
