PolysacDB Lipopolysaccharide 1533

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Klebsiella pneumoniae strain R20/O1

[edit] Basic Structure

N/A

[edit] Proposed functions

It is an important virulence factor

[edit] Antigenic Nature used to produce antibodies

heat-killed Klebsiella pneumoniae strain R20/O1

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Un-named Mab

[edit] Antibody type and class

N/A

[edit] Assay System

ELISA and immunoblotting

[edit] Cross-reactivity

The antibody was able to bind to LPS of clinical isolates of K. pneumoniae, K. oxytoca, K. terrigena and K. planticola but did not bind to LPS of other Gram-negative genera

[edit] Proposed epitopes

This Mab recognized the LPS core

[edit] Proposed Utility

This antibody bound only to those LPS molecules which did not carry an O-antigen and thus this antibody is different from those already published

[edit] Weblink

PubMed

[edit] External Links

• Link to PolysacDB database