PolysacDB Lipopolysaccharide 1230

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Brucella abortus biotype 1

[edit] Basic Structure

LPS carries the A (B. abortus-type) and M (B. melitensis-type) epitopes, respectively. In addition, there is at least one common (C) epitope restricted to the smooth brucellae and a second common epitope (C/Y) shared with Yersinia enterocolitica O:9

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Sheep antisera

[edit] Antibody type and class

N/A

[edit] Assay System

Inihibitory ELISA

[edit] Cross-reactivity

This antibody reacted with both crude LPS and the native hapten component of Brucella

[edit] Proposed epitopes

The epitope was proposed to consist of A and C epitopes

[edit] Proposed Utility

This antisera can be used for the diagnosis of brucellosis in small ruminants and cattle

[edit] Weblink

PubMed Central

[edit] External Links

• IEDB Epitopic Detail

• Link to PolysacDB database