PolysacDB Group B antigen 2409
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Group B antigen
[edit] Carbohydrate Class
Capsular polysaccharide
[edit] Source Microbe
Streptococcus Group B strain M732
[edit] Basic Structure
This polysaccharide had a molecular size > 5 x 106. Its main chemical constituents were sialic acid (24%), galactose (25%), a sugar tentatively identified as heptose (21%), glucose (13%), glucosamine (10%) and mannose (7%)
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
formalin-killed whole cell vaccines
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Antisera
[edit] Antibody type and class
N/A
[edit] Assay System
Capillary precipitin tests, immunodiffusion tests, immunoelectrophoresis
[edit] Cross-reactivity
This antisera cross-reacted with the TCA antigenas well as the EDTA-non pH titrated antigen and the group B antigen extracted with formamide from strain 090R or D136C
[edit] Proposed epitopes
L-rhamnose was the immunodominant sugar for the formamide-extracted B antigen
[edit] Proposed Utility
This antisera has helped determine that two antigens that react identically with each other and with similar specificities of antibody, yet with different immunodominant determinants
