PolysacDB Glycopeptidolipid antigen 1692

From DrugPedia: A Wikipedia for Drug discovery

Jump to: navigation, search


Contents

[edit] Carbohydrate Name

Glycopeptidolipid antigen

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Mycobacterium avium complex serovar 8

[edit] Basic Structure

This antigen is composed of a glycosylated lipopeptide core, fatty acyl-D-phenylalanine-D-allothreonine-D-alanine-L-alaninyl-O-(3,4-di-O-methyl-α-L-rhamnopyranoside), to which a haptenic oligosaccharide is linked at the threonine substituent


[edit] Proposed functions

This oligosaccharide unit is the source of the dominant immunogenicity of members of the M. avium complex, i.e., their characteristic agglutinability and type specificity

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 1105.1

[edit] Antibody type and class

N/A

[edit] Assay System

ELISA, Inhibition assays, dot blot

[edit] Cross-reactivity

N/A

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab can be used for the identification and classification of M. avium isolates. This Mab can be applied directly to bacterial cultures, thus allowing easy, rapid identification of at least half of the M. avium isolates encountered in the clinical laboratory

[edit] Weblink

PubMed Central

[edit] External Links